More Examples

Here you can see Spec work, marketing work, published and unpublished data, Grant and fellowship figures, student work, outreach material, educational content, and data graphics. Note that many of these images are web optimized, and therefore not full resolution. Full resolution images are available upon request.

Quandary Studio has Expertise with several graphic and media tools, including 3D Studio Max, Illustrator, Photoshop, Premiere, and others. In addition, Quandary Studio is skilled in the use of scientific tools, including R and ImageJ, as well as several other proprietary software packages, such as big data tools like Ingenuity Pathway Analysis and DICOM viewers for medical images. We can move fluidly between them and present scientific, medical or other data in an engaging and clear way.

 

Upon request, we can keep precise notes to allow for reproducibility, if necessary. We are also able to present data in a way that is accessible to individuals with deuteranopia and other forms of color-blindness, or to manipulate existing images to be compatible in this way. We're Able to meet your publication guidelines for size and resolution.

In addition to the work presented here, Quandary Studio works with independent contractors, many of whom have impressive portfolios of their own. If you're interested in working with Quandary Studio, please visit the contact page.

Kambin's Triangle
Kambin's Triangle

Visualization of Kambin's Triangle, the target for many spine surgeries originating obliquely.

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Graphic Pentaptych
Graphic Pentaptych

Spec work. Proposal to outline five molecular mechanisms in one illustration.

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Actin Complex
Actin Complex

3D representation of actin in complex with tropomyosin and troponin.

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Nuclear Breakdown
Nuclear Breakdown

A stylized depiction of the major elements in a nucleus.

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PDE4DIP in the NMDA Pathway
PDE4DIP in the NMDA Pathway

Overview of PDE4DIP in the NMDAR-mediated PKA pathway. 3D scene rendered in 2D graphic illustration style.

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Bacterial-Driven Inflammation
Bacterial-Driven Inflammation

Spec work. The role of bacteria in inflammation-driven pain, as mediated by the signaling molecules.

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Cortex Growth
Cortex Growth

Brains in the rodent and primates lineages scale differently in size and neuron number across species. This illustration is meant to quickly communicate this difference.

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Spine Compression Instructional
Spine Compression Instructional

Halted project. Introduction to an educational surgical animation.

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Oligodendrocytes
Oligodendrocytes

Oligodendrocytes. Unpublished data. Used for artistic purposes.

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Outreach, Education, Marketing and Spec Work

7 images

Neuron Number
Neuron Number

Data graphic. The copy number of the "DUF1220" protein domain has been linked to brain size. Neurons in this image were procedurally generated in number and overall sphere size to reflect the copy number found in the genome of the indicated primate species.

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Copy Number Comparison
Copy Number Comparison

Data table used to generate previous data graphic. Calling attention to the striking copy number difference of the DUF1220 sequence in primates.

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Human Genome Copy Number Comparison
Human Genome Copy Number Comparison

Assembly and animation of millions of data points to display the most interesting portion of the human genome. Used in talks and web images.

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Timeline
Timeline

Synthesis of developmental milestones in human brain development. Used in a publication.

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Sequencing Probe Coverage
Sequencing Probe Coverage

High throughput sequencing experiment. Professor P. asked for a way to simultaneously show how well his coverage mapped to his probes, and how comparatively small probe coverage was when compared to repeat elements. This graphic was used in presentations.

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Neuron Number Plot
Neuron Number Plot

Visual way to synthesize many brain size measurements, with neuron number on the X axis and brain mass on the Y axis. Quickly explains why primates cognitively outperform rodents of similar brain size.

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Amp Demand
Amp Demand

Perl, R and 3ds Max were used to visualize amperage demand over time.

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Genetic Position Data
Genetic Position Data

Custom script used with online genomic mapping tools to visualize the genomic positions of 5 different, color-coded elements. The regularity of these different elements with respect to each other is remarkable when presented in this way.

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Conditions Comparison
Conditions Comparison

Many data points in several conditions are summarized in one image.

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Data Visualization

15 images

Chibby Pathway
Chibby Pathway

Proposed mechanism under investigation.

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Human Fetal Brain Tissue
Human Fetal Brain Tissue

Pretest for optimal working conditions: in situ hybridization probe tests. Brightfield, unmodified images.

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Methods
Methods

Publication explanation of analysis pipeline. Graphic simultaneously shows qualitative data side by side and region used in quantification.

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Human Brain RNA Expression
Human Brain RNA Expression

Timeline of gene expression in the developing human brain.

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Rat Cells
Rat Cells

Pretest for optimal working conditions: cell culture blocking solution.

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Cell culture IHC
Cell culture IHC

Immunocytochemistry evaluating two different conditions in cell culture.

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Confocal Cell Culture Imaging
Confocal Cell Culture Imaging

Cell culture evaluated at two conditions. Inset image shows relative brightness of right image when imaged at the same exposure as the left image.

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Transgenic Strategy
Transgenic Strategy

Part of an effort to increase copy number of a specific domain, part 1: construct design.

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Gene Targeting Strategy
Gene Targeting Strategy

Part of an effort to increase copy number of a specific domain, part 2: strategy.

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Grants and Publications

13 images

Mouse Embryos
Mouse Embryos

Objective presentation of two mouse littermates for phenotypic comparison.

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Image Trainer
Image Trainer

Visually highlighting where neurons were found procedurally.

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In situ Hybridization
In situ Hybridization

Localization of an in situ hybridization probe in the ventricular zone of the developing human brain. This is where neurons are born.

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D2B05
D2B05

Summary graphic combining several hundred images of sagittal mouse sections. Broad scale approach maintains context, but still allowed researchers to zoom into crisp detail. Each section is stitched together from many scans into one contiguous image.

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Peripheral Aggregates
Peripheral Aggregates

Green seems to form a protective sheath around dividing cells!

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Neuronal Colocalization
Neuronal Colocalization

Localization of a new antibody to the neural cytoplasm.

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Diencephalon Localization
Diencephalon Localization

Juxtaposition of the telencephalon (front) and diencephalon (middle) of the developing brain.

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Cell Culture Screen
Cell Culture Screen

Screening for undesirable conditions.

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Brain Localization
Brain Localization

Comparison of the developing neocortex in two different lines of mouse.

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Miscellaneous and Unpublished

16 images

Scalpel
Scalpel

Storyboard sketches.

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Jamshidi Needle
Jamshidi Needle

Storyboard sketches.

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Small Canula
Small Canula

Storyboard sketches.

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Vertabrae
Vertabrae

Storyboard sketches.

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Driver
Driver

Storyboard sketches.

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Rod Inserter
Rod Inserter

Storyboard sketches.

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Screw Trajectory
Screw Trajectory

Storyboard sketches.

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Final Shot
Final Shot

Storyboard sketches.

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Screw
Screw

Production pipeline. Actual image, virtual reconstruction, and sketch.

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Personal and Storyboard Artwork

18 images